ALDH1B1
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Aldehyde dehydrogenase 1 family, member B1 | |||||||||||
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Identifiers | |||||||||||
Symbols | ALDH1B1; ALDH5; ALDHX; MGC2230 | ||||||||||
External IDs | OMIM: 100670 MGI: 1919785 HomoloGene: 68079 GeneCards: ALDH1B1 Gene | ||||||||||
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RNA expression pattern | |||||||||||
More reference expression data | |||||||||||
Orthologs | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | 219 | 72535 | |||||||||
Ensembl | ENSG00000137124 | ENSMUSG00000035561 | |||||||||
UniProt | P30837 | Q9CZS1 | |||||||||
RefSeq (mRNA) | NM_000692 | NM_028270 | |||||||||
RefSeq (protein) | NP_000683 | NP_082546 | |||||||||
Location (UCSC) | Chr 9: 38.38 - 38.39 Mb | Chr 4: 45.82 - 45.83 Mb | |||||||||
PubMed search | [1] | [2] |
Aldehyde dehydrogenase X, mitochondrial is an enzyme that in humans is encoded by the ALDH1B1 gene.[1][2]
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.[2]
References
- ^ Hsu LC, Chang WC (Aug 1991). [Expression error: Missing operand for > "Cloning and characterization of a new functional human aldehyde dehydrogenase gene"]. J Biol Chem 266 (19): 12257-65. PMID 2061311.
- ^ a b "Entrez Gene: ALDH1B1 aldehyde dehydrogenase 1 family, member B1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=219.
Further reading
- Yoshida A (1993). [Expression error: Missing operand for > "Molecular genetics of human aldehyde dehydrogenase."]. Pharmacogenetics 2 (4): 139–47. doi: . PMID 1306115.
- Hiraoka LR, Hsu L, Hsieh CL (1995). [Expression error: Missing operand for > "Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13."]. Genomics 25 (1): 323–5. doi: . PMID 7774944.
- Stewart MJ, Malek K, Xiao Q, et al. (1995). [Expression error: Missing operand for > "The novel aldehyde dehydrogenase gene, ALDH5, encodes an active aldehyde dehydrogenase enzyme."]. Biochem. Biophys. Res. Commun. 211 (1): 144–51. doi: . PMID 7779080.
- Maruyama K, Sugano S (1994). [Expression error: Missing operand for > "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides."]. Gene 138 (1-2): 171–4. doi: . PMID 8125298.
- Sherman D, Davé V, Hsu LC, et al. (1994). [Expression error: Missing operand for > "Diverse polymorphism within a short coding region of the human aldehyde dehydrogenase-5 (ALDH5) gene."]. Hum. Genet. 92 (5): 477–80. doi: . PMID 8244338.
- Stewart MJ, Malek K, Crabb DW (1996). [Expression error: Missing operand for > "Distribution of messenger RNAs for aldehyde dehydrogenase 1, aldehyde dehydrogenase 2, and aldehyde dehydrogenase 5 in human tissues."]. J. Investig. Med. 44 (2): 42–6. PMID 8689400.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). [Expression error: Missing operand for > "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library."]. Gene 200 (1-2): 149–56. doi: . PMID 9373149.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). [Expression error: Missing operand for > "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."]. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: . PMID 12477932.
- Humphray SJ, Oliver K, Hunt AR, et al. (2004). [Expression error: Missing operand for > "DNA sequence and analysis of human chromosome 9."]. Nature 429 (6990): 369–74. doi: . PMID 15164053.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). [Expression error: Missing operand for > "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."]. Genome Res. 14 (10B): 2121–7. doi: . PMID 15489334.
- Luo P, Wang A, Payne KJ, et al. (2007). [Expression error: Missing operand for > "Intrinsic retinoic acid receptor alpha-cyclin-dependent kinase-activating kinase signaling involves coordination of the restricted proliferation and granulocytic differentiation of human hematopoietic stem cells."]. Stem Cells 25 (10): 2628–37. doi: . PMID 17628022.
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