Définitions et usages de : beta-Actin - Dictionnaire de anglais sensagent

Beta-actin

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Actin, beta

PDB rendering based on 1atn.

Available structures

1atn, 1c0f, 1c0g, 1d4x, 1dej, 1eqy, 1esv, 1h1v, 1hlu, 1ijj, 1j6z, 1kxp, 1lcu, 1lot, 1m8q, 1ma9, 1mdu, 1mvw, 1nlv, 1nm1, 1nmd, 1nwk, 1o18, 1o19, 1o1a, 1o1b, 1o1c, 1o1d, 1o1e, 1o1f, 1o1g, 1p8z, 1qz5, 1qz6, 1rdw, 1rfq, 1rgi, 1s22, 1sqk, 1t44, 1wua, 1y64, 1yxq, 2a3z, 2a40, 2a41, 2a42, 2a5x, 2asm, 2aso, 2asp, 2btf, 2d1k, 2ff3, 2ff6, 2fxu, 2gwj, 2gwk, 2hf3, 2hf4, 2hmp, 2oan, 2q1n, 2q31, 2q36

Identifiers

Symbols

ACTB; PS1TP5BP1

External IDs

OMIM: 102630 MGI: 87904 HomoloGene: 74383 GeneCards: ACTB Gene

Gene ontology
Molecular function	• nucleotide binding • structural constituent of cytoskeleton • protein binding • ATP binding
Cellular component	• soluble fraction • cytoplasm • cytosol • cytoskeleton • NuA4 histone acetyltransferase complex
Biological process	• cell motility • sensory perception of sound

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 7:
5.53 - 5.54 Mb

Chr 5:
143.17 - 143.17 Mb

PubMed search

[1]

[2]

Beta-actin (gene name ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.^[1]

1 Interactions
2 References
3 Further reading
4 See also

Interactions

Beta-actin has been shown to interact with SPTBN2.^[2]^[3]

References

^ "Entrez Gene: ACTB actin, beta". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60.
^ Mao, B; Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C (May. 2001). [Expression error: Missing operand for > "LDL-receptor-related protein 6 is a receptor for Dickkopf proteins"]. Nature (England) 411 (6835): 321–5. doi:10.1038/35077108. ISSN 0028-0836. PMID 11357114.
^ Holleran, E A; Ligon L A, Tokito M, Stankewich M C, Morrow J S, Holzbaur E L (Sep. 2001). [Expression error: Missing operand for > "beta III spectrin binds to the Arp1 subunit of dynactin"]. J. Biol. Chem. (United States) 276 (39): 36598–605. doi:10.1074/jbc.M104838200. ISSN 0021-9258. PMID 11461920.

Myofilament	Actins (A1, A2, B, C1, G1, G2) Myosins (1A, 1B, 1C, MYH1, MYH2, MYH3, MYH4, MYH6, MYH7, MYH7B, MYH8, MYH9, MYH10, MYH11, MYH13, MYH14, MYH15, MYH16) Tropomodulin (1, 2, 3, 4) · Troponin (T 1 2 3, C 1 2, I 1 2 3) · Tropomyosin (1, 2, 3, 4) other related: Actinin (1, 2, 3, 4) · Arp2/3 complex · actin depolymerizing factors (Cofilin (1, 2) · Destrin) · Gelsolin · Profilin (1, 2)
Other	Wiskott-Aldrich syndrome protein